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7-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one

  • CAS No. 851886-92-5

  • Cat. No. CS-0567133
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one|CS-0567133

Structure of 851886-92-5

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General Information

  • CAS No. 851886-92-5
  • Cat. No. CS-0567133
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉N₃O
  • Molecular Weight 163.18
  • Synonym(s) None
  • SMILES O=C1NC2=CC=CC(N)=C2N1C

Description

7-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one features a fused benzimidazolone core with a strategically positioned amino group enabling direct functionalization. This bench-stable scaffold integrates readily into bioactive molecule design, offering enhanced solubility and metabolic stability in synthetic medicinal chemistry applications.

Application

7-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. The ortho-amino carbonyl motif facilitates cyclization and functionalization reactions, while the methyl group enhances metabolic stability and modulates solubility. Its bench-stable crystalline form supports straightforward handling and purification, making it well-suited for iterative synthesis campaigns and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.81
  • LogP   0.4488
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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