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Structure of 851386-31-7
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2,3-Difluoroisonicotinic acid is a fluorinated pyridine carboxylic acid featuring electron-withdrawing fluorine atoms at the 2 and 3 positions. This configuration enhances acidity and metabolic stability, making it a valuable scaffold in medicinal chemistry for constructing bioactive molecules. The compound serves as a direct precursor in the synthesis of pharmaceutical intermediates and functionalized heterocycles.
2,3-Difluoroisonicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated heterocycles and bioactive molecules. Its ortho-fluorine substituents enhance metabolic stability and modulate electronic properties, while the carboxylic acid group facilitates direct coupling reactions or derivatization. The compound exhibits good bench stability and is compatible with standard amide bond formation protocols, making it well-suited for API development and high-throughput screening campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: