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CS-W001157 4
Total: USD 88.00

5-Bromo-4-methylpyridin-3-amine

  • CAS No. 850892-12-5

  • Cat. No. CS-0043020
  • Purity≥98%
  • MDL No.MFCD07439976

*For research and further manufacturing use only, not for direct human use.

5-Bromo-4-methylpyridin-3-amine|CS-0043020

Structure of 850892-12-5

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General Information

  • CAS No. 850892-12-5
  • Cat. No. CS-0043020
  • Purity ≥98%
  • MDL No. MFCD07439976
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrN₂
  • Molecular Weight 187.04
  • Synonym(s) 5-Bromo-4-methy-pyridin-3-ylamine
  • SMILES CC1=C(N)C=NC=C1Br

Description

5-Bromo-4-methylpyridin-3-amine features a bromine substituent at the 5-position and a methyl group at the 4-position on a pyridine core, enabling selective functionalization in cross-coupling reactions. The electron-deficient pyridine ring enhances reactivity in palladium-catalyzed transformations, while the amine moiety provides a handle for further derivatization. This compound serves as a key intermediate in pharmaceutical synthesis and materials chemistry.

Application

5-Bromo-4-methylpyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromine substituent and electron-deficient pyridine core. The methyl and amino groups provide orthogonal functional handles for further derivatization, while the compound exhibits good bench stability and compatibility with standard purification techniques.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.73472
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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