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CS-W001157 4
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(3-Bromopyridin-2-yl)methanamine hydrochloride

  • CAS No. 1052271-58-5

  • Cat. No. CS-0136640
  • Purity≥97%
  • MDL No.MFCD20923742

*For research and further manufacturing use only, not for direct human use.

(3-Bromopyridin-2-yl)methanamine hydrochloride|CS-0136640

Structure of 1052271-58-5

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General Information

  • CAS No. 1052271-58-5
  • Cat. No. CS-0136640
  • Purity ≥97%
  • MDL No. MFCD20923742
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈BrClN₂
  • Molecular Weight 223.50
  • Synonym(s) 2-(Aminomethyl)-3-bromopyridine hydrochloride
  • SMILES NCC1=NC=CC=C1Br.[H]Cl

Description

This bench-stable hydrochloride salt delivers a versatile pyridylmethylamine scaffold for medicinal chemistry. The bromine substituent enables direct functionalization via cross-coupling, while the protonated amine ensures solubility and ease of handling in aqueous or polar organic media.

Application

(3-Bromopyridin-2-yl)methanamine hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based scaffolds. Its bromo group facilitates palladium-catalyzed cross-coupling reactions, while the primary amine functions as a handle for derivatization or salt formation. The hydrochloride salt enhances solubility and stability, supporting straightforward handling and purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.7246
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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