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CS-W001157 4
Total: USD 88.00

5-Bromo-4,6-dimethylpyridin-3-amine

  • CAS No. 890092-29-2

  • Cat. No. CS-0070543
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Bromo-4,6-dimethylpyridin-3-amine|CS-0070543

Structure of 890092-29-2

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General Information

  • CAS No. 890092-29-2
  • Cat. No. CS-0070543
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉BrN₂
  • Molecular Weight 201.06
  • Synonym(s) 5-Bromo-4,6-dimethyl-pyridin-3-ylamine
  • SMILES BrC(C(C)=C(N)C=N1)=C1C

Description

5-Bromo-4,6-dimethylpyridin-3-amine features a pyridine core with strategically positioned bromo and methyl groups, enabling direct functionalization in cross-coupling reactions. The electron-deficient ring facilitates palladium-catalyzed transformations, while the dimethyl substitution enhances solubility and stability under standard conditions. This scaffold serves as a key building block for bioactive heterocycles and advanced materials.

Application

5-Bromo-4,6-dimethylpyridin-3-amine serves as a versatile building block in medicinal chemistry and catalytic synthesis. The bromine substituent enables palladium-catalyzed cross-coupling reactions, while the pyridin-3-amine functionality provides a robust site for further functionalization. Its methyl groups enhance stability and influence regioselectivity in downstream transformations. This compound is bench-stable, readily purified by crystallization, and functions effectively in standard coupling protocols, making it a practical choice for constructing complex heterocyclic scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H303-H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.04314
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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