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CS-W001157 4
Total: USD 88.00

6-Methoxy-8-nitroquinoline

  • CAS No. 85-81-4

  • Cat. No. CS-0043044
  • Purity≥98%
  • MDL No.MFCD00006802

*For research and further manufacturing use only, not for direct human use.

6-Methoxy-8-nitroquinoline|CS-0043044

Structure of 85-81-4

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General Information

  • CAS No. 85-81-4
  • Cat. No. CS-0043044
  • Purity ≥98%
  • MDL No. MFCD00006802
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈N₂O₃
  • Molecular Weight 204.18
  • Synonym(s) methyl 8-nitro-6-quinolyl ether
  • SMILES O=[N+](C1=C2N=CC=CC2=CC(OC)=C1)[O-]

Description

6-Methoxy-8-nitroquinoline was used in the synthesis of: 6-methoxy-8-aminoquinoline, metabolite of primaquine6-methoxy-8-hydroxylaminoquinoline2-substituted/2,5-disubstituted-6-methoxy-8-nitroquinolines

Synthesis

  • Route1
    • null|null
      96-96-8
    • ~40%
    • In-stock
      6-Methoxy-8-nitroquinoline|CS-0043044
      85-81-4

    References

    • Wyeth Patent: US2003/32645 A1, 2003 ; US 20030032645 A1
  • Route2
    • null|null
      107-02-8
    • null|null
      96-96-8
    • ~17%
    • In-stock
      6-Methoxy-8-nitroquinoline|CS-0043044
      85-81-4

    References

    • Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430
  • Route3

    References

    • Zhurnal Obshchei Khimii, , vol. 3, p. 769,776 Archiv der Pharmazie (Weinheim, Germany), , vol. 271, p. 359,364 Chem. Zentralbl., , vol. 105, # II p. 2227 Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), , vol. 9, p. 304,314 Chem. Zentralbl., , vol. 107, # II p. 1543 Journal of Organic Chemistry, , vol. 12, p. 435 Journal of Organic Chemistry, , vol. 13, p. 937

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.26
  • LogP   2.1516
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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