3-Amino-6-bromo-2-methylpyridine

Name: 3-Amino-6-bromo-2-methylpyridine
Brand: ChemScene
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CAS No. 126325-47-1
Cat. No. CS-D0973
Purity≥98%
MDL No.MFCD03095086

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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3-Amino-6-bromo-2-methylpyridine|CS-D0973

Structure of 126325-47-1

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General Information

CAS No. 126325-47-1
Cat. No. CS-D0973
Purity ≥98%
MDL No. MFCD03095086
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇BrN₂
Molecular Weight 187.04
Synonym(s) 6-Bromo-2-methylpyridin-3-amine
SMILES NC1=CC=C(Br)N=C1C

Description

Pyrrole plays a major role in synthesis of drugs, spices, agrochemicals, dyes, photographic chemicals and perfumes. It plays an important role in the electropolymerisation of macroporous conducting polymer films. It acts as a catalyst for polymerization process; as a standard substance in chromatographic analysis; as corrosion inhibitors and preservatives and as solvents for resins and terpenes. It is utilized to study the hydrogen-bond mediated coupling of 1,2,3-triazole to pyrrole and in the preparation of 1-(4-Chloro-benzoyl)-pyrrole by reacting with 4-Chloro-benzoyl chloride. In Ciamician-Dennstedt rearrangement, It is used to prepare 3-chloropyridine by reacting with dichlorocarbene.

Application

3-Amino-6-bromo-2-methylpyridine serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling direct functionalization at the amino and bromo positions. Its ortho-substituted pyridine core provides enhanced regioselectivity in cross-coupling reactions, while the methyl group contributes to metabolic stability in target scaffolds. The compound exhibits bench-stable handling, tolerates diverse reaction conditions, and facilitates efficient access to biologically relevant heterocycles through palladium-catalyzed transformations.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 38.91
LogP 1.73472
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3-Amino-6-bromo-2-methylpyridine

CAS No. 126325-47-1

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