Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Bromo-4-(2,2-difluorovinyl)benzene,98% (stabilized with TBC)

  • CAS No. 84750-93-6

  • Cat. No. CS-0186320
  • Molecule weight219.03
  • Purity98% (stabilized with TBC)
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Bromo-4-(2,2-difluorovinyl)benzene,98% (stabilized with TBC)|CS-0186320

Structure of 84750-93-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 84750-93-6
  • Cat. No. CS-0186320
  • Purity 98% (stabilized with TBC)
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrF₂
  • Molecular Weight 219.03
  • Synonym(s) 2-(4-Bromophenyl)-1,1-difluoroethylene (stabilized with TBC)
  • SMILES C1=C(C=CC(=C1)Br)C=C(F)F

Description

1-Bromo-4-(2,2-difluorovinyl)benzene features a conjugated difluorovinyl group that enhances electronic effects for cross-coupling applications. The stabilized formulation with TBC ensures improved shelf life and handling safety under standard conditions. This aryl bromide integrates readily into Suzuki-Miyaura and Negishi reactions, delivering high yields in synthetic sequences.

Application

1-Bromo-4-(2,2-difluorovinyl)benzene serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. The 2,2-difluorovinyl group exhibits enhanced stability and predictable reactivity in Suzuki-Miyaura and Stille couplings, while stabilization with TBC ensures shelf-life and handling reliability. Ideal for medicinal chemistry and materials synthesis, it offers high functional group tolerance and straightforward purification.

Synthesis

  • Route1

    References

    • Thomoson, Charles S.; Martinez, Henry; Dolbier Jr., William R. Journal of Fluorine Chemistry, 2013 , vol. 150, p. 53 - 59
  • Route2

    References

    • Li, Qiang; Lin, Jin-Hong; Deng, Zu-Yong; Zheng, Jian; Cai, Ji; Xiao, Ji-Chang Journal of Fluorine Chemistry, 2014 , vol. 163, p. 38 - 41
  • Route3
    • null|null
      115262-00-5
    • In-stock
      4-Bromobenzaldehyde|CS-W001138
      1122-91-4
    • ~52%
    • In-stock
      1-Bromo-4-(2,2-difluorovinyl)benzene,98% (stabilized with TBC)|CS-0186320
      84750-93-6

    References

    • Wang, Fei; Li, Lingchun; Ni, Chuanfa; Hu, Jinbo Beilstein Journal of Organic Chemistry, 2014 , vol. 10, p. 344 - 351

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   0
  • LogP   3.6865
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 84750-93-6 sigma84750-93-6 manufacturer84750-93-6 price84750-93-6 structure84750-93-6 SDSbuy 84750-93-684750-93-6 supplier84750-93-6 uses84750-93-6 molecular weightprice of 84750-93-684750-93-6 chemical name formula of 84750-93-6
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label