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CS-W001157 4
Total: USD 88.00

3-Indolepropionic acid

  • CAS No. 830-96-6

  • Cat. No. CS-W015945
  • Purity≥97%
  • MDL No.MFCD00005660

*For research and further manufacturing use only, not for direct human use.

3-Indolepropionic acid|CS-W015945

Structure of 830-96-6

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General Information

  • CAS No. 830-96-6
  • Cat. No. CS-W015945
  • Purity ≥97%
  • MDL No. MFCD00005660
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁NO₂
  • Molecular Weight None
  • Synonym(s) Indole-3-propionic acid; 3-IPA
  • SMILES C1=CC=CC2=C1C(=C[NH]2)CCC(O)=O

Description

3-Indolepropionic acid is an effective inhibitor of aggregation of misfolded -amyloid protein (Abeta). Three-component one-pot procedure has been reported to assemble 3-indolepropionic acids.Reactant for preparation of:Fluorescent analogues of strigolactonesAnti-tumor agentsMelanocortin receptors ligandsImmunosuppressive agentsIinhibitors of hepatitis C virusHistamine H4 receptor agonistsNR2B/NMDA receptor antagonistsCB1 Antagonist for the treatment of obesityAntibacterial agentsInhibitor of TGF- receptor binding

Synthesis

  • Route1
    • null|null
      160320-11-6
    • ~78%
    • In-stock
      3-Indolepropionic acid|CS-W015945
      830-96-6

    References

    • Ruiz, Miriam; Sanchez, J. Domingo; Lopez-Alvarado, Pilar; Menendez, J. Carlos Tetrahedron, 2012 , vol. 68, # 2 p. 705 - 710
  • Route2
    • Indole, ≥99%|CS-1268948
      120-72-9
    • null|null
      79-10-7
    • ~48%
    • In-stock
      3-Indolepropionic acid|CS-W015945
      830-96-6

    References

    • Cooper, Laura C.; Chicchi, Gary G.; Dinnell, Kevin; Elliott, Jason M.; Hollingworth, Gregory J.; Kurtz, Marc M.; Locker, Karen L.; Morrison, Denise; Shaw, Duncan E.; Tsao, Kwei-Lan; Watt, Alan P.; Williams, Angela R.; Swain, Christopher J. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 9 p. 1233 - 1236
  • Route3
    • null|null
      10184-98-2
    • ~%
    • In-stock
      3-Indolepropionic acid|CS-W015945
      830-96-6

    References

    • Journal of the American Chemical Society, , vol. 67, p. 822

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   53.09
  • LogP   2.1851
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   3

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