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CS-W001157 4
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Boc-NH-PEG1-CH2CH2COOH

  • CAS No. 1260092-44-1

  • Cat. No. CS-0079142
  • Purity≥97%
  • MDL No.MFCD22574796

*For research and further manufacturing use only, not for direct human use.

Boc-NH-PEG1-CH2CH2COOH|CS-0079142

Structure of 1260092-44-1

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General Information

  • CAS No. 1260092-44-1
  • Cat. No. CS-0079142
  • Purity ≥97%
  • MDL No. MFCD22574796
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉NO₅
  • Molecular Weight 233.26
  • Synonym(s) None
  • SMILES CC(C)(OC(NCCOCCC(O)=O)=O)C

Description

Boc-NH-PEG1-CH2CH2COOH features a protected amine terminus linked to a short polyethylene glycol spacer, terminating in a carboxylic acid group. This bifunctional scaffold enables conjugation via amide bond formation while maintaining solubility and stability under standard conditions.

Application

Boc-NH-PEG1-CH₂CH₂COOH serves as a versatile bifunctional linker for conjugation and solid-phase synthesis. The Boc group provides reliable protection of primary amines, while the PEG1 spacer enhances solubility and reduces aggregation. The terminal carboxylic acid enables efficient coupling via amine activation or esterification, facilitating integration into peptide, antibody-drug conjugates, or polymer architectures with minimal steric hindrance.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   1.0024
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

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