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Boc-N-amido-PEG3-acid

  • CAS No. 1347750-75-7

  • Cat. No. CS-0114412
  • Purity≥97%
  • MDL No.MFCD24539476

*For research and further manufacturing use only, not for direct human use.

Boc-N-amido-PEG3-acid|CS-0114412

Structure of 1347750-75-7

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General Information

  • CAS No. 1347750-75-7
  • Cat. No. CS-0114412
  • Purity ≥97%
  • MDL No. MFCD24539476
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₇NO₇
  • Molecular Weight 321.37
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCOCCOCCOCCC(O)=O

Description

Boc-N-amido-PEG3-acid features a trifunctional architecture with a robust Boc-protected amine, a three-ethylene glycol spacer, and a carboxylic acid terminus. This configuration enables site-specific conjugation in bioconjugation workflows while maintaining solubility and stability under standard conditions. The PEG3 chain provides enhanced hydrophilicity and reduced aggregation, facilitating efficient handling in aqueous environments.

Application

Boc-N-amido-PEG3-acid serves as a versatile, bench-stable linker for peptide and small-molecule conjugation. Its PEG3 spacer provides enhanced solubility and reduced aggregation, while the Boc-protected amine enables selective deprotection under mild acidic conditions. The terminal carboxylic acid facilitates coupling to amines via standard amide bond formation, offering reliable functionality in bioconjugation workflows and API scaffold synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   103.32
  • LogP   1.0356
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   12

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