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CS-W001157 4
Total: USD 88.00

1-(2,4-Dimethoxyphenyl)ethanone

  • CAS No. 829-20-9

  • Cat. No. CS-W021196
  • Purity≥97%
  • MDL No.MFCD00008727

*For research and further manufacturing use only, not for direct human use.

1-(2,4-Dimethoxyphenyl)ethanone|CS-W021196

Structure of 829-20-9

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General Information

  • CAS No. 829-20-9
  • Cat. No. CS-W021196
  • Purity ≥97%
  • MDL No. MFCD00008727
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O₃
  • Molecular Weight 180.20
  • Synonym(s) 2',4'-Dimethoxyacetophenone
  • SMILES COC1=CC(OC)=C(C=C1)C(C)=O

Description

1-(2,4-Dimethoxyphenyl)ethanone features a benzoyl core flanked by two methoxy groups, delivering enhanced solubility and electronic modulation. This electron-rich aryl ketone integrates readily into synthetic sequences requiring polarizable aromatic linkages, offering robust stability under standard conditions for use in medicinal chemistry and materials synthesis.

Application

1-(2,4-Dimethoxyphenyl)ethanone serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling the construction of biologically relevant aryl ketones. Its electron-rich aromatic core facilitates electrophilic substitution and participates reliably in Grignard additions, reductions, and coupling reactions. The molecule exhibits good bench stability and is readily purified by recrystallization or flash chromatography, making it well-suited for iterative synthesis workflows.

Synthesis

  • Route1
    • null|null
      108-24-7
    • In-stock
      1,3-Dimethoxybenzene|CS-W018510
      151-10-0
    • ~97%
    • In-stock
      1-(2,4-Dimethoxyphenyl)ethanone|CS-W021196
      829-20-9

    References

    • Green Chemistry, , vol. 15, # 8 p. 2075 - 2080
  • Route2
    • null|null
      89691-57-6
    • ~94%
    • In-stock
      1-(2,4-Dimethoxyphenyl)ethanone|CS-W021196
      829-20-9

    References

    • Tetrahedron Letters, , vol. 52, # 38 p. 4954 - 4956
  • Route3
    • null|null
      75-36-5
    • In-stock
      1,3-Dimethoxybenzene|CS-W018510
      151-10-0
    • ~85%
    • In-stock
      1-(2,4-Dimethoxyphenyl)ethanone|CS-W021196
      829-20-9

    References

    • Synthetic Communications, , vol. 44, # 4 p. 540 - 546

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   1.9064
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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