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CS-W001157 4
Total: USD 88.00

1-(3-Fluoro-4-methoxyphenyl)ethan-1-one

  • CAS No. 455-91-4

  • Cat. No. CS-W017811
  • Purity≥98%
  • MDL No.MFCD00026219

*For research and further manufacturing use only, not for direct human use.

1-(3-Fluoro-4-methoxyphenyl)ethan-1-one|CS-W017811

Structure of 455-91-4

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General Information

  • CAS No. 455-91-4
  • Cat. No. CS-W017811
  • Purity ≥98%
  • MDL No. MFCD00026219
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉FO₂
  • Molecular Weight 168.16
  • Synonym(s) 3'-Fluoro-4'-methoxyacetophenone
  • SMILES CC(C1=CC=C(OC)C(F)=C1)=O

Description

1-(3-Fluoro-4-methoxyphenyl)ethan-1-one features a fluorinated aromatic ring paired with a methoxy group, delivering enhanced electron-withdrawing character and improved solubility. This ketone integrates readily into synthetic pathways requiring stable, functionalized aryl ketones for pharmaceutical intermediates and materials chemistry applications under standard conditions.

Synthesis

  • Route1
    • In-stock
      1-Fluoro-2-methoxybenzene|CS-W011162
      321-28-8
    • null|null
      75-36-5
    • ~94%
    • In-stock
      1-(3-Fluoro-4-methoxyphenyl)ethan-1-one|CS-W017811
      455-91-4

    References

    • G. D. Searle and Co. Patent: US6342510 B1, 2002 ; Location in patent: Page column 28 ;
  • Route2

    References

    • Displaytech, Inc. Patent: US5422037 A1, 1995 ;
  • Route3

    References

    • Yerande, Swapnil G.; Shendage, Deepak M.; Wakchaure, Prasad B.; Phadtare, Ganesh R.; Bhoite, Madhavrao Y.; Gangopadhyay, Ashok Kumar; Nagarajan, Kuppuswamy; Rupp, Richard Helmut Tetrahedron Letters, 2014 , vol. 55, # 15 p. 2426 - 2429

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.0369
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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