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CS-W001157 4
Total: USD 88.00

Sodium 4-fluorobenzenesulfinate

  • CAS No. 824-80-6

  • Cat. No. CS-W005156
  • Purity≥97%
  • MDL No.MFCD03093775

*For research and further manufacturing use only, not for direct human use.

Sodium 4-fluorobenzenesulfinate|CS-W005156

Structure of 824-80-6

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General Information

  • CAS No. 824-80-6
  • Cat. No. CS-W005156
  • Purity ≥97%
  • MDL No. MFCD03093775
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄FNaO₂S
  • Molecular Weight None
  • Synonym(s) P-Fluorobenzenesulfinic acid sodium salt dehydrate
  • SMILES FC1=CC=C(S(O[Na])=O)C=C1

Description

Sodium 4-fluorobenzenesulfinate delivers a fluorinated aryl sulfinate anion with enhanced stability and solubility in aqueous and polar organic media. This bench-stable reagent enables direct sulfination reactions, integrating cleanly into synthetic sequences requiring traceless sulfur transfer or late-stage functionalization.

Application

Sodium 4-fluorobenzenesulfinate serves as a stable, bench-ready sulfinate source for transition-metal-catalyzed cross-coupling reactions. It facilitates efficient C–S bond formation under mild conditions, exhibits good functional group tolerance, and enables direct access to fluorinated aryl sulfones—key motifs in pharmaceutical and agrochemical scaffolds. Its crystalline nature supports straightforward handling and purification.

Synthesis

  • Route1

    References

    • Acta Chemica Scandinavica, Series A: Physical and Inorganic Chemistry, , vol. A30, # 8 p. 579 - 585
  • Route2
    • null|null
      139131-31-0
    • ~46%
    • In-stock
      Sodium 4-fluorobenzenesulfinate|CS-W005156
      824-80-6
    • null|null
      65332-44-7

    References

    • Journal of Organic Chemistry, , vol. 57, # 9 p. 2594 - 2599
  • Route3
    • null|null
      139131-32-1
    • ~%
    • In-stock
      Sodium 4-fluorobenzenesulfinate|CS-W005156
      824-80-6

    References

    • Journal of Organic Chemistry, , vol. 57, # 9 p. 2594 - 2599

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   0.9484
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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