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Structure of 82257-15-6
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4-Methoxypyridine-3-carbaldehyde features a pyridine ring bearing both a methoxy group at the 4-position and a formyl substituent at the 3-position, creating a polar, electron-deficient heterocyclic scaffold. This arrangement enables efficient coupling in transition-metal-catalyzed reactions and facilitates incorporation into bioactive molecule frameworks. The aldehyde functionality supports rapid derivatization under mild conditions, while the methoxy group enhances solubility and stability.
4-Methoxypyridine-3-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles through standard coupling and functional group transformation protocols. Its pyridine core provides enhanced solubility and metabolic stability, while the aldehyde group offers high reactivity for imine formation, reductive amination, and Ugi-type multicomponent reactions. Bench-stable and compatible with common protecting groups, it facilitates streamlined synthesis of drug candidates and advanced intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: