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CS-W001157 4
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(3-Cyclopropoxyphenyl)boronic acid

  • CAS No. 808140-97-8

  • Cat. No. CS-0135502
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3-Cyclopropoxyphenyl)boronic acid|CS-0135502

Structure of 808140-97-8

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General Information

  • CAS No. 808140-97-8
  • Cat. No. CS-0135502
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BO₃
  • Molecular Weight 177.99
  • Synonym(s) (3-cyclopropyloxyphenyl)boronic acid
  • SMILES OB(C1=CC=CC(OC2CC2)=C1)O

Description

(3-Cyclopropoxyphenyl)boronic acid features a cyclopropoxy group positioned ortho to the boronic acid moiety, enhancing solubility and stability in aqueous media. This configuration supports efficient Suzuki-Miyaura cross-coupling reactions under mild conditions, enabling reliable carbon-carbon bond formation in complex molecule synthesis.

Application

(3-Cyclopropoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its cyclopropoxy substituent provides enhanced metabolic stability and favorable lipophilicity for medicinal chemistry applications. The boronic acid moiety exhibits excellent bench stability, tolerates common functional groups, and facilitates straightforward purification—making it ideal for iterative synthesis of complex aryl scaffolds in drug discovery and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   -0.0924
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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