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CS-W001157 4
Total: USD 88.00

(2-Cyclopropoxyphenyl)boronic acid

  • CAS No. 225517-86-2

  • Cat. No. CS-0135493
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-Cyclopropoxyphenyl)boronic acid|CS-0135493

Structure of 225517-86-2

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General Information

  • CAS No. 225517-86-2
  • Cat. No. CS-0135493
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BO₃
  • Molecular Weight 177.99
  • Synonym(s) Boronic acid, [2-(cyclopropyloxy)phenyl]-
  • SMILES OB(C1=CC=CC=C1OC2CC2)O

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, offering enhanced stability and solubility in polar aprotic solvents. The cyclopropoxy substituent imparts favorable electronic tuning and steric profile, enabling efficient functionalization of aryl targets without significant decomposition.

Application

(2-Cyclopropoxyphenyl)boronic acid serves as a reliable building block for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of biaryl scaffolds under mild conditions. Its stability in air and moisture facilitates handling and purification, while the cyclopropoxy group offers predictable electronic modulation and orthogonality in complex molecule synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   -0.0924
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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