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CS-W001157 4
Total: USD 88.00

2-Aminopropanamide hydrochloride

  • CAS No. 80222-96-4

  • Cat. No. CS-0036447
  • Purity≥97%
  • MDL No.MFCD00066144

*For research and further manufacturing use only, not for direct human use.

2-Aminopropanamide hydrochloride|CS-0036447

Structure of 80222-96-4

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General Information

  • CAS No. 80222-96-4
  • Cat. No. CS-0036447
  • Purity ≥97%
  • MDL No. MFCD00066144
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₉ClN₂O
  • Molecular Weight 124.57
  • Synonym(s) (+/-)-alaninamide hydrochloride
  • SMILES CC(N)C(N)=O.Cl

Description

2-Aminopropanamide hydrochloride is a bench-stable, moisture-tolerant amide derivative featuring a primary amine and a carboxamide group on a propanamide scaffold. This bifunctional molecule integrates readily into peptide synthesis workflows and serves as a key building block for bioactive compound libraries.

Application

2-Aminopropanamide hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to β-amino acid derivatives and peptidomimetics. Its amine and amide functionalities offer orthogonal reactivity for coupling and derivatization, while the hydrochloride salt enhances bench stability and solubility in aqueous and polar organic media. This compound facilitates straightforward incorporation into heterocyclic scaffolds and peptide-like architectures, supporting scalable synthesis workflows in API development.

Synthesis

  • Route1

    References

    • Kato, Yasuo; Asano, Yasuhisa; Nakazawa, Akiko; Kondo, Kiyosi Tetrahedron, 1989 , vol. 45, # 18 p. 5743 - 5754

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H319
Precautionary Statements : P261-P264-P272-P280-P302+P352-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   70.1
  • LogP   0.29067
  • H_Acceptors   2
  • H_Donors   3
  • Rotatable_Bonds   1

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