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CS-W001157 4
Total: USD 88.00

H-D-Ala-NH2.HCl

  • CAS No. 71810-97-4

  • Cat. No. CS-W022738
  • Purity≥98%
  • MDL No.MFCD00039093

*For research and further manufacturing use only, not for direct human use.

H-D-Ala-NH2.HCl|CS-W022738

Structure of 71810-97-4

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General Information

  • CAS No. 71810-97-4
  • Cat. No. CS-W022738
  • Purity ≥98%
  • MDL No. MFCD00039093
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₉ClN₂O
  • Molecular Weight 124.57
  • Synonym(s) H-D-Ala-Nh2·Hcl
  • SMILES C[C@@H](N)C(N)=O.[H]Cl

Description

H-D-Ala-NH2·HCl delivers a deuterated alanine derivative with enhanced metabolic stability, featuring a terminal amine for facile conjugation. The hydrochloride salt ensures excellent solubility and shelf-life under standard laboratory conditions, making it ideal for peptide synthesis and isotopic labeling applications.

Application

H-D-Ala-NH₂·HCl serves as a stable, bench-ready building block for peptide synthesis, enabling efficient incorporation of D-alanine residues into bioactive sequences. Its zwitterionic form enhances solubility and simplifies purification, while the protected amine facilitates orthogonal coupling strategies in solid-phase and solution-phase workflows. Widely used in medicinal chemistry for modulating peptide stability and conformational rigidity.

Synthesis

  • Route1
    • null|null
      1336-21-6
    • In-stock
      tert-Butoxycarbonyl-DL-alanine|CS-D1433
      3744-87-4
    • null|null
      541-41-3
    • ~73%
    • In-stock
      H-D-Ala-NH2.HCl|CS-W022738
      71810-97-4

    References

    • SmithKline Beechman Corp. Patent: US5438118 A1, 1995 ; US 5438118 A

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   69.11
  • LogP   -0.7593
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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