Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]acetamide

  • CAS No. 1220220-21-2

  • Cat. No. CS-D1265
  • Purity≥97%
  • MDL No.MFCD11878181

*For research and further manufacturing use only, not for direct human use.

N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]acetamide|CS-D1265

Structure of 1220220-21-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1220220-21-2
  • Cat. No. CS-D1265
  • Purity ≥97%
  • MDL No. MFCD11878181
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₉BN₂O₃
  • Molecular Weight 262.11
  • Synonym(s) N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)acetamide
  • SMILES CC(NC1=NC=CC(B2OC(C)(C)C(C)(C)O2)=C1)=O

Description

N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]acetamide features a pyridine-linked boronate ester enabling efficient Suzuki-Miyaura coupling. The tetramethyl-dioxaborolane moiety confers excellent stability and compatibility with aqueous conditions, while the acetamide group enhances solubility and facilitates downstream functionalization in medicinal chemistry and materials synthesis.

Application

N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]acetamide serves as a versatile boronate building block for palladium-catalyzed cross-coupling reactions. The pyridylboronate moiety enables efficient Suzuki-Miyaura coupling under mild conditions, while the acetamide group provides stability and facilitates purification. This compound exhibits excellent bench stability, functional group tolerance, and compatibility with diverse reaction scopes in medicinal chemistry and materials synthesis.

Synthesis

  • Route1

    References

    • US2013/165464 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   60.45
  • LogP   1.3392
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1220220-21-2 sigma1220220-21-2 manufacturer1220220-21-2 price1220220-21-2 structure1220220-21-2 SDSbuy 1220220-21-21220220-21-2 supplier1220220-21-2 uses1220220-21-2 molecular weightprice of 1220220-21-21220220-21-2 chemical name formula of 1220220-21-2
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label