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Structure of 957062-72-5
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Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylate features a pyridine-2-carboxylate scaffold paired with a stable boronate handle. This bench-stable reagent integrates seamlessly into Suzuki-Miyaura coupling protocols, enabling efficient construction of biaryl architectures under mild conditions. The tetramethylcyclopentadienone-derived boronate group ensures high functional group tolerance and reliable reactivity.
Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylate serves as a versatile boronate ester building block in palladium-catalyzed cross-coupling reactions. Its pyridine carboxylate functionality enables direct incorporation into biaryl and heterocyclic scaffolds common in medicinal chemistry. The tetramethyl-substituted dioxaborolane moiety ensures excellent bench stability, low hydrolytic sensitivity, and compatibility with diverse reaction conditions, facilitating efficient functionalization of complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: