Lot numbers can be found on the outside label of a product:
N-hydroxynaphthalimide
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CAS No. 7797-81-1
- Cat. No. CS-0155692
- Purity≥96%
- MDL No.MFCD00065062
*For research and further manufacturing use only, not for direct human use.
Structure of 7797-81-1
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General Information
- CAS No. 7797-81-1
- Cat. No. CS-0155692
- Purity ≥96%
- MDL No. MFCD00065062
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₂H₇NO₃
- Molecular Weight 213.19
- Synonym(s) N-Hydroxy-1,8-naphthalenedicarboximide
- SMILES C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)O
Description
N-hydroxynaphthalimide delivers a reactive hydroxyl group tethered to a rigid, electron-deficient naphthalene core, enabling efficient coupling in amide bond formation. This bench-stable scaffold integrates readily into synthetic workflows requiring selective activation under mild conditions.
Application
N-Hydroxynaphthalimide serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized naphthalene scaffolds. Its hydroxyl group facilitates direct derivatization and conjugation reactions, while the imide moiety provides robust stability and compatibility with standard purification techniques. Widely employed in the synthesis of fluorescent probes and pharmaceutical intermediates, it functions effectively in both solution-phase and solid-phase workflows, offering predictable reactivity and high bench utility for medicinal and process chemists.
Synthesis
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Route1
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81-84-5 - ~91%
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In-stock
7797-81-1
References
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Ranadive, V. B.; Samant, S. D. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 2 p. 102 - 106
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Route2
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In-stock
81-83-4 - ~%
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In-stock
7797-81-1
References
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Synthetic Communications, , vol. 31, # 5 p. 741 - 748
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Route3
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40153-25-1
- ~%
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In-stock
7797-81-1
References
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Journal of the Chemical Society, , p. 3518
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Quality Control
Computational Chemistry Data
- TPSA 57.61
- LogP 1.825
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 0
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