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CS-W001157 4
Total: USD 88.00

4-Aminonaphthalimide

  • CAS No. 1742-95-6

  • Cat. No. CS-0003831
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD00006921

*For research and further manufacturing use only, not for direct human use.

4-Aminonaphthalimide|CS-0003831

Structure of 1742-95-6

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General Information

  • CAS No. 1742-95-6
  • Cat. No. CS-0003831
  • Purity ≥97%
  • MDL No. MFCD00006921
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₈N₂O₂
  • Molecular Weight None
  • Synonym(s) 4-Amino-1,8-Naphthalimide
  • SMILES O=C1NC(C2=CC=C(N)C3=CC=CC1=C23)=O

Description

Inhibiting poly(ADP-ribose) polymerase activity at submicromolar concentrations, 4-Amino-1,8-naphthalimide (CAS 1742-95-6) disrupts DNA repair cascades in cancer cell lines through targeted enzyme suppression.

Synthesis

  • Route1

    References

    • Alexiou, Michael; Tyman, John; Wilson, Ian Tetrahedron Letters, 1981 , vol. 22, # 24 p. 2303 - 2306
  • Route2
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    • ~%
    • In-stock
      4-Aminonaphthalimide|CS-0003831
      1742-95-6

    References

    • DE602944 , ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 21, p. 370 US2006017 , ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335-H302
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   72.19
  • LogP   1.3056
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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