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CS-W001157 4
Total: USD 88.00

Thiophene-2-thiol

  • CAS No. 7774-74-5

  • Cat. No. CS-W016596
  • Molecule weight116.20
  • Purity≥95%
  • MDL No.MFCD00051666

*For research and further manufacturing use only, not for direct human use.

Thiophene-2-thiol|CS-W016596

Structure of 7774-74-5

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General Information

  • CAS No. 7774-74-5
  • Cat. No. CS-W016596
  • Purity ≥95%
  • MDL No. MFCD00051666
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄S₂
  • Molecular Weight 116.20
  • Synonym(s) 2-Thienyl mercaptan
  • SMILES SC1=CC=CS1

Application

Thiophene-2-thiol serves as a versatile building block in heterocyclic synthesis, enabling efficient access to thienyl-containing scaffolds prevalent in pharmaceuticals and functional materials. Its reactive thiol group facilitates conjugate additions, metal-catalyzed couplings, and disulfide formation, while the thiophene core provides stability and π-conjugation. The compound exhibits bench-stable handling and compatibility with diverse functional groups, making it well-suited for iterative synthetic strategies and scale-up applications.

Synthesis

  • Route1
    • null|null
      1227941-25-4
    • ~86%
    • In-stock
      Thiophene-2-thiol|CS-W016596
      7774-74-5

    References

    • SUVEN LIFE SCIENCES LIMITED; CHINNAPILLAI, Rajendiran; PERIYANDI, Nagarajan; JASTI, Venkateswarlu Patent: WO2010/61398 A1, 2010 ; Location in patent: Page/Page column 18-19; 24-25 ;
  • Route2
    • null|null
      188290-36-0
    • ~71%
    • In-stock
      Thiophene-2-thiol|CS-W016596
      7774-74-5

    References

    • Anisimov, A.V.; Panov, S. M.; Egorov, A. M.; Viktorova, E. A. Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, p. 367 - 369 Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 2 p. 408 - 411
  • Route3
    • null|null
      87947-35-1
    • ~%
    • In-stock
      Thiophene-2-thiol|CS-W016596
      7774-74-5

    References

    • US5041461 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.0368
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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