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CS-W001157 4
Total: USD 88.00

2-Pyrimidinethiol

  • CAS No. 131242-36-9

  • Cat. No. CS-0928501
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Pyrimidinethiol|CS-0928501

Structure of 131242-36-9

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Description

2-Pyrimidinethiol offers a reactive thiol group positioned at the 2-position of a pyrimidine core, enabling direct incorporation into nucleophilic conjugation workflows. This scaffold combines moderate electron density with enhanced stability under standard handling conditions, facilitating efficient coupling in synthetic and bioconjugation applications.

Application

2-Pyrimidinethiol serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrimidine-based scaffolds prevalent in medicinal chemistry. Its thiol functionality facilitates reliable conjugation reactions and metal coordination, while the aromatic core ensures stability under standard bench conditions. The compound functions effectively in nucleophilic substitutions and transition-metal-catalyzed couplings, offering predictable reactivity and straightforward purification.

General Information

  • CAS No. 131242-36-9
  • Cat. No. CS-0928501
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄N₂S
  • Molecular Weight 112.15
  • Synonym(s) None
  • SMILES SC1=NC=CC=N1

Computational Chemistry Data

  • TPSA   25.78
  • LogP   0.7653
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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