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Structure of 1450-86-8
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Pyrimidine-4(3H)-thione features a labile thione tautomer stabilized by aromaticity, enabling direct participation in nucleophilic substitution and metal coordination. This heterocyclic scaffold integrates readily into bioactive molecules and serves as a key motif in pharmaceutical intermediates and ligand design.
Pyrimidine-4(3H)-thione serves as a versatile building block in heterocyclic synthesis, enabling efficient access to medicinally relevant pyrimidine scaffolds. Its thione functionality facilitates nucleophilic addition and metal-catalyzed coupling reactions, offering robust reactivity under standard conditions. The compound exhibits good bench stability and compatibility with common protecting groups, supporting its use in multi-step syntheses of agrochemicals and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: