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2-Chlorothiophene-3-carbaldehyde

  • CAS No. 14345-98-3

  • Cat. No. CS-0089614
  • Purity≥95%
  • MDL No.MFCD08694817

*For research and further manufacturing use only, not for direct human use.

2-Chlorothiophene-3-carbaldehyde|CS-0089614

Structure of 14345-98-3

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General Information

  • CAS No. 14345-98-3
  • Cat. No. CS-0089614
  • Purity ≥95%
  • MDL No. MFCD08694817
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃ClOS
  • Molecular Weight None
  • Synonym(s) 2-Chlorothiophene-3-carboxaldehyde
  • SMILES O=CC1=C(Cl)SC=C1

Description

2-Chlorothiophene-3-carbaldehyde features a thiophene core with chlorine and aldehyde functionalities positioned for selective coupling reactions. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and functional materials, offering enhanced reactivity under standard conditions.

Application

2-Chlorothiophene-3-carbaldehyde serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the 3-position via nucleophilic addition or transition-metal-catalyzed coupling. Its electrophilic aldehyde group exhibits good bench stability and compatibility with common protecting groups, facilitating efficient assembly of complex thiophene-based scaffolds relevant to pharmaceutical and agrochemical research.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.214
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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