Pyridine-2-thiol

Name: Pyridine-2-thiol
Brand: ChemScene
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CAS No. 73018-10-7
Cat. No. CS-0145370
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 73018-10-7

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Description

Pyridine-2-thiol delivers a reactive thiol group positioned ortho to a basic pyridine nitrogen, enabling efficient coordination in metal complexation and serving as a key ligand in catalytic systems. This bench-stable, moisture-tolerant compound integrates readily into synthetic pathways requiring redox-active sulfur functionality.

Application

Pyridine-2-thiol serves as a versatile heterocyclic building block in synthetic organic chemistry, enabling the construction of thioether-linked scaffolds and metal-chelating motifs. Its reactive thiol group facilitates conjugate additions, nucleophilic substitutions, and coordination to transition metals, while the pyridine ring provides ortho-directing capability and enhanced solubility. Bench-stable and compatible with standard purification protocols, it functions effectively in multi-step syntheses requiring functional group tolerance and predictable reactivity.

General Information

CAS No. 73018-10-7
Cat. No. CS-0145370
Purity ≥98%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₅NS
Molecular Weight 111.16
Synonym(s) 2-Mercaptopyridine
SMILES SC1=NC=CC=C1

Computational Chemistry Data

TPSA 12.89
LogP 1.3703
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

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Pyridine-2-thiol

CAS No. 73018-10-7

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