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Structure of 77156-85-5
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Ethyl 4-chloro-7-methoxyquinoline-3-carboxylate features a quinoline core with orthogonal electron-withdrawing (chloro) and electron-donating (methoxy) substituents, enabling tailored reactivity in cross-coupling and heterocyclic synthesis. The ester handle facilitates derivatization under standard conditions.
Ethyl 4-chloro-7-methoxyquinoline-3-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions at the C4 chloro position. The methoxy group at C7 provides electronic modulation and enhances solubility, while the ester functionality supports subsequent transformations such as hydrolysis or reduction. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: