Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-Chloro-[1,2,4]triazolo[4,3-b]pyridazine

  • CAS No. 28593-24-0

  • Cat. No. CS-W005315
  • Purity≥97%
  • MDL No.MFCD00219047

*For research and further manufacturing use only, not for direct human use.

6-Chloro-[1,2,4]triazolo[4,3-b]pyridazine|CS-W005315

Structure of 28593-24-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 28593-24-0
  • Cat. No. CS-W005315
  • Purity ≥97%
  • MDL No. MFCD00219047
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃ClN₄
  • Molecular Weight 154.56
  • Synonym(s) 6-Chloro-1,2,4-triazolo[4,3-b]pyridazine
  • SMILES ClC1=NN2C(C=C1)=NN=C2

Description

6-Chloro-[1,2,4]triazolo[4,3-b]pyridazine is a heterocyclic scaffold featuring a chlorine substituent at the 6-position, enhancing its reactivity in nucleophilic substitution and cross-coupling processes. This electron-deficient triazolopyridazine core integrates readily into bioactive molecules, offering favorable stability under standard bench conditions for medicinal chemistry applications.

Application

6-Chloro-[1,2,4]triazolo[4,3-b]pyridazine serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical research. Its chloro substituent enables facile nucleophilic displacement and palladium-catalyzed coupling reactions, facilitating the construction of complex triazolopyridazine scaffolds. The compound exhibits good bench stability and compatibility with common reaction conditions, supporting efficient functionalization in multi-step syntheses.

Synthesis

  • Route1
    • In-stock
      3-Chloro-6-hydrazinylpyridazine|CS-W002246
      17284-97-8
    • null|null
      243116-57-6
    • ~71%
    • In-stock
      6-Chloro-[1,2,4]triazolo[4,3-b]pyridazine|CS-W005315
      28593-24-0

    References

    • AMOREPACIFIC CORPORATION; INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY; CRYSTALGENOMICS, INC. Patent: WO2008/69500 A1, 2008 ; Location in patent: Page/Page column 9-10; 24 ;
  • Route2

    References

    • Sunder, Shyam; Peet, Norton P. Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1527 - 1529
  • Route3
    • In-stock
      3-Chloro-6-hydrazinylpyridazine|CS-W002246
      17284-97-8
    • null|null
      103272-74-8
    • ~87%
    • In-stock
      6-Chloro-[1,2,4]triazolo[4,3-b]pyridazine|CS-W005315
      28593-24-0

    References

    • Kocevar; Susin; Polanc Synthesis, 1993 , # 8 p. 773 - 774

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317
Precautionary Statements : P261-P272-P280-P302+P352-P363-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   43.08
  • LogP   0.7777
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 28593-24-0 sigma28593-24-0 manufacturer28593-24-0 price28593-24-0 structure28593-24-0 SDSbuy 28593-24-028593-24-0 supplier28593-24-0 uses28593-24-0 molecular weightprice of 28593-24-028593-24-0 chemical name formula of 28593-24-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label