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Structure of 13720-94-0
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Ethyl 4-chloroquinoline-3-carboxylate features a quinoline core with strategic chlorination at the 4-position and an ester-functionalized C3 site. This combination imparts enhanced electron-withdrawing character and facilitates downstream derivatization in synthetic medicinal chemistry. The compound exhibits good stability under standard conditions and serves as a key scaffold for developing bioactive molecules, particularly in antimalarial and kinase inhibitor research.
Ethyl 4-chloroquinoline-3-carboxylate serves as a versatile building block in the synthesis of quinoline-based pharmaceuticals and agrochemicals. Its chloro group at the 4-position enables palladium-catalyzed cross-coupling reactions, while the ester functionality supports selective reduction and derivatization. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: