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CS-W001157 4
Total: USD 88.00

5'-Fluorospiro[cyclopropane-1,3'-indolin]-2'-one

  • CAS No. 769965-95-9

  • Cat. No. CS-0054214
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5'-Fluorospiro[cyclopropane-1,3'-indolin]-2'-one|CS-0054214

Structure of 769965-95-9

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General Information

  • CAS No. 769965-95-9
  • Cat. No. CS-0054214
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈FNO
  • Molecular Weight 177.18
  • Synonym(s) 5'-fluoro-Spiro[cyclopropane-1,3'-[3H]indol]-2'(1'H)-one
  • SMILES O=C(C12CC1)NC3=C2C=C(F)C=C3

Synthesis

  • Route1
    • null|null
      769965-94-8
    • ~98%
    • In-stock
      5'-Fluorospiro[cyclopropane-1,3'-indolin]-2'-one|CS-0054214
      769965-95-9

    References

    • IRM LLC Patent: WO2005/18568 A2, 2005 ; Location in patent: Page/Page column 36 ; WO 2005/018568 A2
  • Route2
    • In-stock
      5-Fluoro-2-oxoindoline|CS-W002914
      56341-41-4
    • null|null
      106-93-4
    • ~%
    • In-stock
      5'-Fluorospiro[cyclopropane-1,3'-indolin]-2'-one|CS-0054214
      769965-95-9

    References

    • NOVARTIS AG; ATKINSON, Benjamin; BEATTIE, David; CULSHAW, Andrew James; DALE, James; DEVEREUX, Nicholas James; MCKENNA, Jeffrey Patent: WO2011/92293 A2, 2011 ; Location in patent: Page/Page column 85 ; WO 2011/092293 A1
  • Route3
    • null|null
      769965-93-7
    • ~%
    • In-stock
      5'-Fluorospiro[cyclopropane-1,3'-indolin]-2'-one|CS-0054214
      769965-95-9

    References

    • Tully, David C.; Liu, Hong; Chatterjee, Arnab K.; Alper, Phil B.; Williams, Jennifer A.; Roberts, Michael J.; Mutnick, Daniel; Woodmansee, David H.; Hollenbeck, Thomas; Gordon, Perry; Chang, Jonathan; Tuntland, Tove; Tumanut, Christine; Li, Jun; Harris, Jennifer L.; Karanewsky, Donald S. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 19 p. 5107 - 5111

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   1.8094
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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