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Structure of 13861-75-1
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Spiro[cyclopropane-1,3'-indolin]-2'-one features a rigid spirocyclic scaffold integrating a cyclopropane ring with an indolinone core, delivering enhanced structural rigidity and metabolic stability. This architecture supports precise molecular positioning in target engagement, enabling efficient incorporation into bioactive compounds for medicinal chemistry applications.
Spiro[cyclopropane-1,3'-indolin]-2'-one serves as a rigid, three-dimensional building block for medicinal chemistry and natural product synthesis. Its spirocyclic architecture imparts conformational stability and enhances target binding affinity. The ketone functionality enables nucleophilic addition and reduction, while the indolinone core supports downstream functionalization. Bench-stable and amenable to standard purification methods, it functions effectively in multi-step syntheses requiring stereochemical control and structural diversity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: