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CS-W001157 4
Total: USD 88.00

Pyrazine-2,5-diamine

  • CAS No. 768386-37-4

  • Cat. No. CS-0019308
  • Purity≥95%
  • MDL No.MFCD09835012

*For research and further manufacturing use only, not for direct human use.

Pyrazine-2,5-diamine|CS-0019308

Structure of 768386-37-4

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General Information

  • CAS No. 768386-37-4
  • Cat. No. CS-0019308
  • Purity ≥95%
  • MDL No. MFCD09835012
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆N₄
  • Molecular Weight 110.12
  • Synonym(s) 2,5-Pyrazinediamine(9CI)
  • SMILES NC1=NC=C(N)N=C1

Description

Pyrazine-2,5-diamine delivers a rigid, electron-rich heteroaromatic scaffold ideal for constructing bioactive molecules and functional materials. This diamine integrates readily into conjugated systems, offering enhanced solubility and stability under standard conditions. Its dual amine functionality enables straightforward derivatization in synthetic workflows.

Application

Pyrazine-2,5-diamine serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its diamino functionality enables straightforward incorporation into pharmaceutical scaffolds via amide coupling, Suzuki-Miyaura cross-coupling, or electrophilic substitution. The molecule exhibits good bench stability and facilitates the construction of biologically relevant pyrazine-based frameworks due to its predictable reactivity and compatibility with diverse functional groups.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   77.82
  • LogP   -0.359
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   0

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