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Structure of 32111-28-7
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N-Methylpyrazin-2-amine features a pyrazine core with a methylated amine at the 2-position, delivering enhanced solubility and metabolic stability. This nitrogen-rich heterocycle integrates readily into pharmaceutical scaffolds and serves as a key building block in medicinal chemistry for targeted ligand design.
N-Methylpyrazin-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to pyrazine-based scaffolds through standard functionalization. Its methylated nitrogen enhances solubility and metabolic stability while maintaining reactivity for palladium-catalyzed cross-couplings. The compound exhibits bench-stable handling and facilitates rapid diversification via nucleophilic substitution or further alkylation, making it well-suited for high-throughput synthesis of API candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: