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CS-W001157 4
Total: USD 88.00

Methyl 2-aminobutanoate hydrochloride

  • CAS No. 7682-18-0

  • Cat. No. CS-W018067
  • Purity≥95%
  • MDL No.MFCD00058295

*For research and further manufacturing use only, not for direct human use.

Methyl 2-aminobutanoate hydrochloride|CS-W018067

Structure of 7682-18-0

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General Information

  • CAS No. 7682-18-0
  • Cat. No. CS-W018067
  • Purity ≥95%
  • MDL No. MFCD00058295
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂ClNO₂
  • Molecular Weight 153.61
  • Synonym(s) Methyl DL-2-Aminobutyrate Hydrochloride
  • SMILES CCC(N)C(OC)=O.Cl

Description

Methyl 2-aminobutanoate hydrochloride serves as a key chiral building block in peptide synthesis and medicinal chemistry. This bench-stable, moisture-tolerant derivative features a protected amine group that enables straightforward functionalization and incorporation into complex molecular architectures under standard conditions.

Application

Methyl 2-aminobutanoate hydrochloride serves as a versatile chiral building block in peptide synthesis and medicinal chemistry. Its well-defined stereochemistry and amine functionality enable reliable coupling reactions, while the methyl ester group facilitates selective transformations. The hydrochloride salt enhances solubility and stability under standard bench conditions, simplifying handling and purification in multi-step syntheses.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      Boc-L-2-aminobutanoic acid|CS-W019939
      34306-42-8
    • ~97%
    • In-stock
      Methyl 2-aminobutanoate hydrochloride|CS-W018067
      7682-18-0

    References

    • Fuchs, Klaus; Eickmeier, Christian; Heine, Niklas; Peters, Stefan; Dorner-Ciossek, Cornelia; Handschuh, Sandra; Nar, Herbert; Klinder, Klaus Patent: US2010/144681 A1, 2010 ; Location in patent: Page/Page column 67 ; US 20100144681 A1
  • Route2
    • null|null
      67-56-1
    • H-Abu-OH Levetiracetam Impurity|CS-0213953
      1492-24-6
    • ~99%
    • In-stock
      Methyl 2-aminobutanoate hydrochloride|CS-W018067
      7682-18-0

    References

    • Hildenbrand, Simone; Baqi, Younis; Mueller, Christa E. Journal of Labelled Compounds and Radiopharmaceuticals, 2012 , vol. 55, # 1 p. 48 - 51
  • Route3
    • null|null
      861889-32-9
    • ~90%
    • In-stock
      Methyl 2-aminobutanoate hydrochloride|CS-W018067
      7682-18-0

    References

    • Desrosiers, Jean-Nicolas; Cote, Alexandre; Charette, Andre B. Tetrahedron, 2005 , vol. 61, # 26 p. 6186 - 6192

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.3185
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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