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CS-W001157 4
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1-Ethyl-3-methyl-1H-imidazol-3-ium glycinate

  • CAS No. 766537-74-0

  • Cat. No. CS-0832100
  • Purity≥98%
  • MDL No.MFCD18632569

*For research and further manufacturing use only, not for direct human use.

1-Ethyl-3-methyl-1H-imidazol-3-ium glycinate|CS-0832100

Structure of 766537-74-0

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General Information

  • CAS No. 766537-74-0
  • Cat. No. CS-0832100
  • Purity ≥98%
  • MDL No. MFCD18632569
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₅N₃O₂
  • Molecular Weight 185.22
  • Synonym(s) None
  • SMILES [O-]C(CN)=O.CCN1C=[N+](C)C=C1

Description

This imidazolium glycinate salt combines a protic ionic liquid cation with a zwitterionic anion, delivering enhanced solubility and thermal stability. The ethyl and methyl substituents on the imidazolium ring modulate polarity and reactivity, while the glycinate moiety offers hydrogen-bonding capacity and biocompatibility. This structure enables efficient phase-transfer behavior in catalytic systems and supports green chemistry applications through recyclable solvent design.

Application

1-Ethyl-3-methyl-1H-imidazol-3-ium glycinate serves as a stable, bench-friendly ionic liquid that facilitates efficient peptide coupling and catalytic transformations. Its imidazolium cation enables strong hydrogen bonding and solvation of polar intermediates, while the glycinate anion offers mild nucleophilicity and compatibility with diverse functional groups. This dual functionality supports robust reactivity in standard synthetic workflows, including amide bond formation and metal-catalyzed cross-couplings, with straightforward purification and high operational stability under ambient conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   74.96
  • LogP   -1.9725
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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