1-(4-Chlorophenyl)pyrrolidin-2-one

Name: 1-(4-Chlorophenyl)pyrrolidin-2-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 7661-33-8
Cat. No. CS-0037155
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(4-Chlorophenyl)pyrrolidin-2-one|CS-0037155

Structure of 7661-33-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

1-(4-Chlorophenyl)pyrrolidin-2-one features a chlorinated aryl group attached to a saturated lactam core, conferring enhanced lipophilicity and metabolic stability. This scaffold integrates readily into bioactive molecule design, particularly in medicinal chemistry campaigns targeting CNS disorders and kinase inhibition. The electron-withdrawing chlorine substituent modulates electronic distribution across the ring system, enabling precise tuning of reactivity and binding affinity.

Application

1-(4-Chlorophenyl)pyrrolidin-2-one serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard functionalization and coupling reactions. Its bench-stable pyrrolidinone core exhibits excellent tolerance to diverse reaction conditions, facilitating efficient derivatization at the C2 position and accommodating further substitution on the aryl ring. This scaffold is commonly employed in the synthesis of pharmaceutical intermediates due to its favorable reactivity profile and compatibility with standard purification methods.

General Information

CAS No. 7661-33-8
Cat. No. CS-0037155
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₀ClNO
Molecular Weight 195.65
Synonym(s) 1-(4-Chlorophenyl)-2-pyrrolidinone
SMILES C1CC(=O)N(C1)C2=CC=C(C=C2)Cl

Computational Chemistry Data

TPSA 20.31
LogP 2.4668
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

1-(4-Chlorophenyl)pyrrolidin-2-one sigma1-(4-Chlorophenyl)pyrrolidin-2-one manufacturer1-(4-Chlorophenyl)pyrrolidin-2-one price1-(4-Chlorophenyl)pyrrolidin-2-one structure1-(4-Chlorophenyl)pyrrolidin-2-one SDSbuy 1-(4-Chlorophenyl)pyrrolidin-2-one1-(4-Chlorophenyl)pyrrolidin-2-one supplier1-(4-Chlorophenyl)pyrrolidin-2-one uses1-(4-Chlorophenyl)pyrrolidin-2-one molecular weightprice of 1-(4-Chlorophenyl)pyrrolidin-2-one1-(4-Chlorophenyl)pyrrolidin-2-one chemical name formula of 1-(4-Chlorophenyl)pyrrolidin-2-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-(4-Chlorophenyl)pyrrolidin-2-one

CAS No. 7661-33-8

Recommended Products