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CS-W001157 4
Total: USD 88.00

3-Methoxy-2-methylpyridin-4(1H)-one

  • CAS No. 76015-11-7

  • Cat. No. CS-W018315
  • Purity≥97%
  • MDL No.MFCD03093994

*For research and further manufacturing use only, not for direct human use.

3-Methoxy-2-methylpyridin-4(1H)-one|CS-W018315

Structure of 76015-11-7

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General Information

  • CAS No. 76015-11-7
  • Cat. No. CS-W018315
  • Purity ≥97%
  • MDL No. MFCD03093994
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO₂
  • Molecular Weight 139.15
  • Synonym(s) 4(1H)-pyridinone, 3-methoxy-2-methyl-
  • SMILES O=C1C(OC)=C(C)NC=C1

Description

3-Methoxy-2-methylpyridin-4(1H)-one features a pyridinone core with strategically positioned methoxy and methyl groups, enhancing solubility and metabolic stability. This scaffold integrates readily into medicinal chemistry campaigns, offering a robust platform for targeted bioactive molecule development.

Application

3-Methoxy-2-methylpyridin-4(1H)-one serves as a versatile heterocyclic building block in medicinal chemistry, offering a readily accessible scaffold for late-stage functionalization. Its pyridinone core enables robust coordination in metal-catalyzed couplings, while the methoxy and methyl groups provide orthogonal handles for selective derivatization. The compound exhibits excellent bench stability and facilitates efficient purification, making it well-suited for high-throughput synthesis and process-scale applications.

Synthesis

  • Route1

    References

    • Ma, Yongmin; Luo, Wei; Quinn, Peter J.; Liu, Zudong; Hider, Robert C. Journal of Medicinal Chemistry, 2004 , vol. 47, # 25 p. 6349 - 6362
  • Route2
    • Maltol, ≥99.0%|CS-1268661
      118-71-8
    • ~%
    • In-stock
      3-Methoxy-2-methylpyridin-4(1H)-one|CS-W018315
      76015-11-7

    References

    • Journal of Medicinal Chemistry, , vol. 47, # 25 p. 6349 - 6362

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   42.09
  • LogP   0.69192
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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