Methyl 4-hydroxy-2-methoxybenzoate

Name: Methyl 4-hydroxy-2-methoxybenzoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 28478-46-8
Cat. No. CS-0042916
Purity≥97%
MDL No.MFCD06203815

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 4-hydroxy-2-methoxybenzoate|CS-0042916

Structure of 28478-46-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 28478-46-8
Cat. No. CS-0042916
Purity ≥97%
MDL No. MFCD06203815
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₀O₄
Molecular Weight None
Synonym(s) 4-HYDROXY-2-METHOXY-BENZOIC ACID METHYL ESTER
SMILES COC(=O)C1=CC=C(O)C=C1OC

Description

Methyl 4-hydroxy-2-methoxybenzoate features a phenolic hydroxyl group flanked by a methoxy substituent and ester functionality, enabling selective derivatization in synthetic routes. This ortho-substituted methyl ester exhibits enhanced solubility in organic solvents and stability under standard bench conditions, making it suitable for use in pharmaceutical intermediates and agrochemical synthesis.

Application

Methyl 4-hydroxy-2-methoxybenzoate serves as a versatile building block in medicinal chemistry and natural product synthesis. Its ortho-methoxy and para-hydroxyl groups enable selective derivatization, while the ester functionality supports facile hydrolysis or coupling reactions. The compound exhibits good bench stability and is readily purified by recrystallization or flash chromatography, facilitating integration into multi-step synthetic sequences.

Synthesis

Route1
- 845307-11-1
- ~%
- In-stock
  
  28478-46-8
References
- Legrand, Sacha; Nordlander, Goeran; Nordenhem, Henrik; Borg-Karlson, Anna-Karin; Unelius, C. Rikard Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2004 , vol. 59, # 7 p. 829 - 835
Route2
- 61539-61-5
- 922-67-8
- ~%
- In-stock
  
  28478-46-8
References
- Danishefsky,S. et al. Journal of the American Chemical Society, 1979 , vol. 101, p. 7001 - 7008
Route3
- 28478-45-7
- ~99%
- In-stock
  
  28478-46-8
References
- Merck and Co., Inc. Patent: US5665719 A1, 1997 ; US 5665719 A

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 55.76
LogP 1.1874
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

Methyl 4-hydroxy-2-methoxybenzoate sigmaMethyl 4-hydroxy-2-methoxybenzoate manufacturerMethyl 4-hydroxy-2-methoxybenzoate priceMethyl 4-hydroxy-2-methoxybenzoate structureMethyl 4-hydroxy-2-methoxybenzoate SDSbuy Methyl 4-hydroxy-2-methoxybenzoateMethyl 4-hydroxy-2-methoxybenzoate supplierMethyl 4-hydroxy-2-methoxybenzoate usesMethyl 4-hydroxy-2-methoxybenzoate molecular weightprice of Methyl 4-hydroxy-2-methoxybenzoateMethyl 4-hydroxy-2-methoxybenzoate chemical name formula of Methyl 4-hydroxy-2-methoxybenzoate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 4-hydroxy-2-methoxybenzoate

CAS No. 28478-46-8

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words