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CS-W001157 4
Total: USD 88.00

Pantoprazole impurity 42

  • CAS No. 107512-34-5

  • Cat. No. CS-0050928
  • Purity≥98%
  • MDL No.MFCD16610605

*For research and further manufacturing use only, not for direct human use.

Pantoprazole impurity 42|CS-0050928

Structure of 107512-34-5

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General Information

  • CAS No. 107512-34-5
  • Cat. No. CS-0050928
  • Purity ≥98%
  • MDL No. MFCD16610605
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈ClNO
  • Molecular Weight 157.60
  • Synonym(s) None
  • SMILES COC1=C(C)N=CC=C1Cl

Description

4-Chloro-3-methoxy-2-methylpyridine features a strategically positioned chloro group and methoxy substituent on a pyridine core, enabling selective coupling reactions. The methyl group enhances electron density at C2, facilitating functionalization under mild conditions. This scaffold offers robust stability and compatibility with diverse reaction environments.

Application

4-Chloro-3-methoxy-2-methylpyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its reactive chloropyridine functionality. The methoxy and methyl groups provide orthogonal sites for further functionalization, while the compound exhibits excellent bench stability and ease of purification—ideal for modular synthesis of heterocyclic scaffolds and API intermediates.

Synthesis

  • Route1
    • 3-Methoxy-2-methylpyridin-4(1H)-one Pantoprazole Impurity|CS-0229223
      76015-11-7
    • ~96%
    • In-stock
      Pantoprazole impurity 42|CS-0050928
      107512-34-5

    References

    • Maharvi, Ghulam M.; Bharucha, Adil E.; Fauq, Abdul H. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2808 - 2811
  • Route2
    • Maltol, ≥99.0%|CS-1268661
      118-71-8
    • ~%
    • In-stock
      Pantoprazole impurity 42|CS-0050928
      107512-34-5

    References

    • Kuhler; Fryklund; Bergman; Weilitz; Lee; Larsson Journal of Medicinal Chemistry, 1995 , vol. 38, # 25 p. 4906 - 4916
  • Route3

    References

    • Ohta, Akihiro; Takahashi, Nobuhiro; Shirokoma, Yasuko Heterocycles, 1990 , vol. 30, # 2 p. 875 - 884

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   2.05202
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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