Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2,2-Dimethylcyclopropanecarboxylic acid

  • CAS No. 75885-59-5

  • Cat. No. CS-W005115
  • Purity≥95%
  • MDL No.MFCD04972493

*For research and further manufacturing use only, not for direct human use.

2,2-Dimethylcyclopropanecarboxylic acid|CS-W005115

Structure of 75885-59-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 75885-59-5
  • Cat. No. CS-W005115
  • Purity ≥95%
  • MDL No. MFCD04972493
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀O₂
  • Molecular Weight 114.14
  • Synonym(s) cyclopropanecarboxylic acid, 2,2-dimethyl-
  • SMILES CC1(C)CC1C(O)=O

Description

2,2-Dimethylcyclopropanecarboxylic acid features a rigid cyclopropane ring with two methyl groups at the geminal position, imparting exceptional steric congestion. This structural constraint enhances stability and influences reactivity in synthetic transformations. The carboxylic acid group enables direct functionalization or coupling reactions, making it a valuable scaffold for medicinal chemistry and materials science applications.

Application

2,2-Dimethylcyclopropanecarboxylic acid serves as a robust building block for strained cyclopropane-containing scaffolds in medicinal chemistry. Its carboxylic acid functionality enables direct derivatization into amides, esters, and acyl chlorides, while the geminal dimethyl substitution enhances stability and modulates lipophilicity. The rigid cyclopropane core imparts conformational constraint, facilitating precise spatial orientation in target molecules. This compound functions effectively in standard coupling reactions and is compatible with diverse protecting group strategies, making it a valuable tool for synthesizing bioactive analogs and complex heterocycles.

Synthesis

  • Route1
    • 2,2-Dimethylcyclopropanecarbonitrile|CS-0153796
      5722-11-2
    • ~82%
    • In-stock
      2,2-Dimethylcyclopropanecarboxylic acid|CS-W005115
      75885-59-5

    References

    • Wills, Max T.; Wills, Irene E.; Dollen, Lawrence Von; Butler, Barry L.; Porter, John; Anderson, Arthur G. Journal of Organic Chemistry, 1980 , vol. 45, # 12 p. 2489 - 2498
  • Route2
    • (2,2-Dimethylcyclopropyl)methanol|CS-0238975
      930-50-7
    • ~75%
    • In-stock
      2,2-Dimethylcyclopropanecarboxylic acid|CS-W005115
      75885-59-5

    References

    • Allen; Fenwick; Henry-Riyad; Tidwell Journal of Organic Chemistry, 2001 , vol. 66, # 17 p. 5759 - 5765
  • Route3

    References

    • Journal of Organic Chemistry, , vol. 45, # 12 p. 2489 - 2498

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.1171
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2,2-Dimethylcyclopropanecarboxylic acid sigma2,2-Dimethylcyclopropanecarboxylic acid manufacturer2,2-Dimethylcyclopropanecarboxylic acid price2,2-Dimethylcyclopropanecarboxylic acid structure2,2-Dimethylcyclopropanecarboxylic acid SDSbuy 2,2-Dimethylcyclopropanecarboxylic acid2,2-Dimethylcyclopropanecarboxylic acid supplier2,2-Dimethylcyclopropanecarboxylic acid uses2,2-Dimethylcyclopropanecarboxylic acid molecular weightprice of 2,2-Dimethylcyclopropanecarboxylic acid2,2-Dimethylcyclopropanecarboxylic acid chemical name formula of 2,2-Dimethylcyclopropanecarboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label