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Pyrrolidin-2-imine (hydrochloride) Tipiracil Impurity

  • CAS No. 7544-75-4

  • Cat. No. CS-0229316
  • Purity≥98%
  • MDL No.MFCD00790772

*For research and further manufacturing use only, not for direct human use.

Pyrrolidin-2-imine (hydrochloride) Tipiracil  Impurity|CS-0229316

Structure of 7544-75-4

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General Information

  • CAS No. 7544-75-4
  • Cat. No. CS-0229316
  • Purity ≥98%
  • MDL No. MFCD00790772
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉ClN₂
  • Molecular Weight 120.58
  • Synonym(s) 3,4-Dihydro-2H-pyrrol-5-amine hydrochloride
  • SMILES NC1=NCCC1.Cl

Synthesis

  • Route1

    References

    • GENESTE, Hervé; TURNER, Sean Colm; OCHSE, Michael; DRESCHER, Karla; BLACK, Lawrence A.; JANTOS, Katja Patent: US2014/148461 A1, 2014 ; Location in patent: Paragraph 0354-0355 ;
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    • Pyrrolidin-2-imine (hydrochloride) Tipiracil  Impurity|CS-0229316
      7544-75-4

    References

    • Callahan, James F.; Burgess, Joelle L.; Fornwald, James A.; Gaster, Laramie M.; Harling, John D.; Harrington, Frank P.; Heer, Jag; Kwon, Chet; Lehr, Ruth; Mathur; Olson, Barbara A.; Weinstock, Joseph; Laping, Nicholas J. Journal of Medicinal Chemistry, 2002 , vol. 45, # 5 p. 999 - 1001

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.38
  • LogP   0.5592
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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