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CS-W001157 4
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3-Bromo-2-(bromomethyl)pyridine

  • CAS No. 754131-60-7

  • Cat. No. CS-0137384
  • Purity≥97%
  • MDL No.MFCD09999976
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Bromo-2-(bromomethyl)pyridine|CS-0137384

Structure of 754131-60-7

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Description

3-Bromo-2-(bromomethyl)pyridine features a bromomethyl group flanked by a pyridine ring and a bromine at the 3-position, enabling dual electrophilic reactivity. This bifunctional scaffold integrates readily into synthetic sequences requiring orthogonal functionalization, particularly in medicinal chemistry and heterocyclic derivatization workflows.

Application

3-Bromo-2-(bromomethyl)pyridine serves as a versatile bifunctional building block in synthetic chemistry, enabling efficient construction of pyridine-based heterocycles and pharmaceutical intermediates. The bromomethyl group facilitates nucleophilic substitution and Suzuki-type coupling reactions, while the 3-bromo substituent supports palladium-catalyzed cross-coupling. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for iterative synthesis workflows in medicinal chemistry and process development.

General Information

  • CAS No. 754131-60-7
  • Cat. No. CS-0137384
  • Purity ≥97%
  • MDL No. MFCD09999976
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅Br₂N
  • Molecular Weight 250.92
  • Synonym(s) None
  • SMILES BrCC1=NC=CC=C1Br

Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.739
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group :
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501

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