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Structure of 39806-89-8
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4-Ethynyl-1-methyl-1H-pyrazole is a bench-stable, moisture-tolerant heterocycle featuring a terminal alkyne group poised for efficient Cu-catalyzed coupling reactions. This pyrazole scaffold integrates seamlessly into bioactive molecules and functional materials, offering high reactivity in click chemistry applications while maintaining excellent handling properties under standard conditions.
4-Ethynyl-1-methyl-1H-pyrazole serves as a versatile building block in transition-metal-catalyzed coupling reactions, enabling efficient access to conjugated heterocyclic architectures. Its terminal alkyne functionality exhibits high compatibility with Sonogashira and copper-catalyzed Glaser-type couplings, while the pyrazole core provides stability and moderate electron-donating character. The molecule demonstrates excellent bench stability, ease of purification, and functional group tolerance, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P405-P501
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Lot numbers can be found on the outside label of a product: