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CS-W001157 4
Total: USD 88.00

H-Leu-OMe.HCl

  • CAS No. 7517-19-3

  • Cat. No. CS-W017143
  • Purity≥97%
  • MDL No.MFCD00012494

*For research and further manufacturing use only, not for direct human use.

H-Leu-OMe.HCl|CS-W017143

Structure of 7517-19-3

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General Information

  • CAS No. 7517-19-3
  • Cat. No. CS-W017143
  • Purity ≥97%
  • MDL No. MFCD00012494
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₆ClNO₂
  • Molecular Weight 181.66
  • Synonym(s) None
  • SMILES CC(C[C@@](N)([H])C(OC)=O)C.Cl

Description

H-Leu-OMe.HCl is a bench-stable, moisture-tolerant dipeptide building block featuring a methyl ester terminus and protonated N-terminal amine. This protected leucine derivative integrates readily into peptide synthesis workflows, offering efficient coupling under standard conditions while minimizing side reactions.

Synthesis

  • Route1
    • null|null
      67-56-1
    • L-Leucine, 99%|CS-1269060
      61-90-5
    • ~96%
    • In-stock
      H-Leu-OMe.HCl|CS-W017143
      7517-19-3

    References

    • McKerrow, Jason D.; Al-Rawi, Jasim M. A.; Brooks, Peter Synthetic Communications, 2010 , vol. 40, # 8 p. 1161 - 1179
  • Route2
    • L-Leucine, 99%|CS-1269060
      61-90-5
    • ~10%
    • In-stock
      H-Leu-OMe.HCl|CS-W017143
      7517-19-3

    References

    • Takeda Chemical Industries, Ltd. Patent: US6420415 B1, 2002 ;
  • Route3
    • null|null
      112018-28-7
    • ~97%
    • In-stock
      H-Leu-OMe.HCl|CS-W017143
      7517-19-3

    References

    • Grieco, Paul A.; Clark, Jerry D. Journal of Organic Chemistry, 1990 , vol. 55, # 8 p. 2271 - 2272

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.9546
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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