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CS-W001157 4
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Methyl (tert-butoxycarbonyl)-D-leucinate

  • CAS No. 133467-01-3

  • Cat. No. CS-0096869
  • Purity≥97%
  • MDL No.MFCD11041224

*For research and further manufacturing use only, not for direct human use.

Methyl (tert-butoxycarbonyl)-D-leucinate|CS-0096869

Structure of 133467-01-3

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General Information

  • CAS No. 133467-01-3
  • Cat. No. CS-0096869
  • Purity ≥97%
  • MDL No. MFCD11041224
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₃NO₄
  • Molecular Weight 245.32
  • Synonym(s) None
  • SMILES CC(C)C[C@H](C(OC)=O)NC(OC(C)(C)C)=O

Description

Methyl (tert-butoxycarbonyl)-D-leucinate serves as a protected D-leucine derivative featuring a tert-butoxycarbonyl group that ensures stability and ease of handling. This ester integrates readily into peptide synthesis workflows, enabling selective N-terminal protection during chain elongation. The methyl ester moiety allows for straightforward deprotection under mild acidic conditions.

Application

Methyl (tert-butoxycarbonyl)-D-leucinate serves as a protected D-leucine derivative enabling efficient peptide synthesis. The tert-butyl carbamate (Boc) group provides orthogonal protection compatible with standard deprotection protocols, while the methyl ester facilitates selective hydrolysis or coupling reactions. This stable, bench-friendly building block supports iterative chain elongation in solid-phase and solution-phase peptide methodologies, offering predictable reactivity and straightforward purification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.63
  • LogP   2.0988
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   4

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