H-Val-OMe.HCl

Name: H-Val-OMe.HCl
Brand: ChemScene
Availability: InStock
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CAS No. 6306-52-1
Cat. No. CS-W010793
Purity≥97%
MDL No.MFCD00012497

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 6306-52-1

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General Information

CAS No. 6306-52-1
Cat. No. CS-W010793
Purity ≥97%
MDL No. MFCD00012497
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₄ClNO₂
Molecular Weight 167.63
Synonym(s) None
SMILES CC([C@@](N)([H])C(OC)=O)C.Cl

Description

H-Val-OMe.HCl is a bench-stable, moisture-tolerant dipeptide building block featuring a methyl ester-protected valine residue. This derivative enables efficient incorporation into peptide chains under standard coupling conditions, delivering enhanced solubility and handling convenience in synthetic workflows.

Application

H-Val-OMe·HCl serves as a stable, bench-ready building block for peptide synthesis, enabling efficient coupling of valine in both solution-phase and solid-phase workflows. Its methyl ester functionality facilitates downstream derivatization, while the hydrochloride salt enhances solubility and handling. The protected side chain ensures compatibility with standard deprotection protocols and supports orthogonal functional group manipulation in complex sequence assembly.

Synthesis

Route1
- 67-56-1
- In-stock
  
  72-18-4
- ~99%
- In-stock
  
  6306-52-1
References
- Ananthi, Nallamuthu; Balakrishnan, Umesh; Velmathi, Sivan ARKIVOC (Gainesville, FL, United States), 2010 , vol. 2010, # 11 p. 370 - 379,10
Route2
- 67-56-1
- 17498-50-9
- ~%
- In-stock
  
  6306-52-1
References
- European Journal of Medicinal Chemistry, , vol. 68, p. 253 - 259
Route3
- In-stock
  
  72-18-4
- ~%
- In-stock
  
  6306-52-1
References
- Tetrahedron, , vol. 63, # 41 p. 10282 - 10289

Safety Information

Download SDS

GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

TPSA 52.32
LogP 0.5645
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Valine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids C-ProtectedAmino Acids

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H-Val-OMe.HCl

CAS No. 6306-52-1

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