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Structure of 75091-93-9
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trans-4-(Trifluoromethyl)cyclohexanol features a sterically defined trifluoromethyl group at the equatorial position, delivering enhanced metabolic stability and lipophilicity. This bench-stable derivative integrates readily into medicinal chemistry libraries, offering a rigid, electron-deficient scaffold for probing target interactions in drug discovery.
trans-4-(Trifluoromethyl)cyclohexanol serves as a stable, bench-accessible building block for medicinal chemistry and asymmetric synthesis. Its rigid cyclohexane framework with a stereodefined trifluoromethyl group enables precise control over molecular conformation and lipophilicity. The hydroxyl functionality facilitates derivatization via standard esterification, etherification, or oxidation protocols, while the trifluoromethyl moiety imparts enhanced metabolic stability and membrane permeability—key attributes in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: