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CS-W001157 4
Total: USD 88.00

4-(Trifluoromethyl)cyclohexanol

  • CAS No. 30129-18-1

  • Cat. No. CS-W005856
  • Molecule weight168.16
  • Purity≥95%
  • MDL No.MFCD00102144

*For research and further manufacturing use only, not for direct human use.

4-(Trifluoromethyl)cyclohexanol|CS-W005856

Structure of 30129-18-1

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General Information

  • CAS No. 30129-18-1
  • Cat. No. CS-W005856
  • Purity ≥95%
  • MDL No. MFCD00102144
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁F₃O
  • Molecular Weight 168.16
  • Synonym(s) 4-(Trifluoromethyl)cyclohexanol (cis
  • SMILES OC1CCC(C(F)(F)F)CC1

Description

4-(Trifluoromethyl)cyclohexanol features a trifluoromethyl group at the para position of a cyclohexanol scaffold, delivering enhanced lipophilicity and metabolic stability. This bench-stable, moisture-tolerant compound integrates readily into synthetic routes for bioactive molecules, serving as a key building block in medicinal chemistry and agrochemical development.

Application

4-(Trifluoromethyl)cyclohexanol serves as a valuable chiral building block in medicinal chemistry, offering a stable, bench-accessible cyclohexanolic scaffold with enhanced lipophilicity and metabolic stability due to the trifluoromethyl group. It functions as a versatile intermediate in the synthesis of bioactive molecules, participating reliably in esterification, etherification, and oxidation reactions while maintaining compatibility with common protecting group strategies.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.0998
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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